Depolarization signatures map gold nanorods within biological tissue Supplementary Information - Depolarization signatures map gold nanorods within biological tissue
نویسندگان
چکیده
Harvard Medical School, Boston, MA, USA Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA Department of Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA
منابع مشابه
Depolarization signatures map gold nanorods within biological tissue
Owing to their electromagnetic properties, tunability and biocompatibility, gold nanorods (GNRs) are being investigated as multifunctional probes for a range of biomedical applications. However, detection beyond the reach of traditional fluorescence and two-photon approaches and quantitation of their concentration in biological tissue remain challenging tasks in microscopy. Here we show how the...
متن کاملTunable depolarized light scattering from gold and gold/silver nanorods.
We combine the fabrication of Au and Au/Ag core/shell nanorods (NRs), as well as experimental measurements of vis-NIR extinction, unpolarized, and cross-polarized light scattering spectra, with T-matrix and separation-of-variables simulations, to gain insight into the relation between the morphology/composition of nanoparticles and their isotropic and anisotropic optical responses. Using severa...
متن کاملGold nanorods for fluorescence lifetime imaging in biology.
Two-photon luminescence (TPL) from gold nanorods shows considerable potential in biological imaging. We study the imaging of gold nanorods in Madin-Darby canine kidney (MDCK) cells using fluorescence lifetime imaging microscopy (FLIM). FLIM provides images with better contrast and sensitivity than intensity imaging. The characteristic fluorescence lifetime of gold nanorods is found to be less t...
متن کاملIn vivo photoacoustic molecular imaging with simultaneous multiple selective targeting using antibody-conjugated gold nanorods.
The use of gold nanorods for photoacoustic molecular imaging with simultaneous multiple targeting is reported. Multiple targeting is done by utilizing the tunable optical absorption property of gold nanorods. This technique allows multiple molecular signatures to be obtained by simply switching laser wavelength. HER2 and EGFR were chosen as the primary target molecules for examining two cancer ...
متن کاملIn vitro toxicity and bioimaging studies of gold nanorods formulations coated with biofunctional thiol-PEG molecules and Pluronic block copolymers
In this work, we investigated the cytotoxicity, colloidal stability and optical property of gold nanorods before and after functionalizing them with thiolated PEG and Pluronic triblock copolymer (PEO-PPO-PEO) molecules. The morphology of functionalized gold nanorods was characterized by UV-visible absorption spectroscopy, transmission electron microscopy, and dynamic light scattering. Solution ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017